Welcome to Week 2! Three money picks connected in Week 1: the San Francisco 49ers, New York Giants, and New York Jets all cashed as medium risk plays. Congratulations to everyone who rode those dogs! Check out this week’s preliminary picks below. Let’s keep the momentum going in Week 2!

Here are this week’s updated base picks.

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Keep an eye on our $ Score metrics to uncover the top-value picks and maximize your points.

See our NFL Weekly Confidence Pool Picks: The Basics post or How to make confidence pool picks for beginners – 2023 update video for for more info on how to use these picks.

[Preliminary Picks on 09/15/2026]

Higher Risk Picks (Bright Green):

• Detroit Lions over Buffalo Bills: 37% win probability, 9% pick-rate
• Arizona Cardinals over Seattle Seahawks: 32% win probability, 8% pick-rate
• Minnesota Vikings over Chicago Bears: 30% win probability, 8% pick-rate
• Indianapolis Colts over Kansas City Chiefs: 27% win probability, 4% pick-rate
• Tennessee Titans over Philadelphia Eagles: 26% win probability, 2% pick-rate
• Cleveland Browns over Tampa Bay Buccaneers: 23% win probability, 1% pick-rate
• New Orleans Saints over Baltimore Ravens: 23% win probability, 2% pick-rate

Medium Risk Picks (Dark Green):

• Washington Commanders over Dallas Cowboys: 35% win probability, 17% pick-rate

As the 2026 season rolls into Week 2, now’s the time to sharpen your strategy and make every pick count. Good luck out there!

Suggested picks by risk

See our NFL Weekly Confidence Pool Picks: The Basics post or How to make NFL Pick ‘Em Confidence Pool Picks – step by step video for for more info.